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Study Uncovers Role of Ultraviolet Radiation in Development of Rare Leukemia in the Skin News

Study Uncovers Role of Ultraviolet Radiation in Development of Rare Leukemia in the Skin

A change of scenery can restore one's outlook, but for some precancerous cells, a journey from the caves of the bone marrow to the sunny climes of the skin can trigger genetic changes that are a harbinger of cancer, according to a new study by researchers at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Broad Institute of MIT and Harvard.
New Clinical Tool for Clonal Hematopoiesis Identifies Patients at High Risk for Blood Cancer News

New Clinical Tool for Clonal Hematopoiesis Identifies Patients at High Risk for Blood Cancer

A new clinical tool developed by a team of researchers led by the Dana-Farber Cancer Institute pinpoints which Clonal hematopoiesis patients are at highest risk for cancer progression.
High Concentrations of Immune Cells Within Tumors Associated with Longer Patient Survival News

High Concentrations of Immune Cells Within Tumors Associated with Longer Patient Survival

ImmunoPROFILE: A prospective implementation of clinically validated, quantitative immune cell profiling test identifies tumor-infiltrating CD8+ and PD-1+ cell densities as prognostic biomarkers across a 2,023 patient pan-cancer cohort treated with different therapies
Clinical Trial Shows That Adding Bevacizumab to Targeted Drug and Chemotherapy Produces Striking Activity Against HER2-Positive Metastatic Gastroesophageal Adenocarcinoma News

Clinical Trial Shows That Adding Bevacizumab to Targeted Drug and Chemotherapy Produces Striking Activity Against HER2-Positive Metastatic Gastroesophageal Adenocarcinoma

Long-term results and ctDNA correlatives for CAPOX BETR: A multi-center phase II trial of capecitabine, oxaliplatin, bevacizumab and trastuzumab for previously untreated HER2 positive metastatic gastroesophageal adenocarcinoma
Dana-Farber Researchers Chart a Course for Understanding, Preventing, and Treating Young-Onset Colorectal Cancer News

Dana-Farber Researchers Chart a Course for Understanding, Preventing, and Treating Young-Onset Colorectal Cancer

Colorectal cancer among young people is increasing globally and rapidly. Experts expect it to become the leading cause of cancer death in individuals aged 20-49 in the U.S. by the year 2030.
Finding Pancreatic Cancer Earlier - How Dana-Farber is Transforming the Narrative in the Early Detection and Treatment of a Stubborn Cancer News

Finding Pancreatic Cancer Earlier - How Dana-Farber is Transforming the Narrative in the Early Detection and Treatment of a Stubborn Cancer

Pancreatic cancer is notoriously difficult to treat. It's commonly discovered at an advanced stage with distant metastases. But innovations in genetic testing and early detection at Dana-Farber are transforming this narrative — giving patients renewed hope for successful long-term treatment and even cures.
Study Unravels a Cause of Resistance to Novel Drug in Patients with Acute Leukemia News

Study Unravels a Cause of Resistance to Novel Drug in Patients with Acute Leukemia

A new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells to reveal one of their schemes for resisting the drug, investigators at Dana-Farber Cancer Institute and other research centers report in a new pair of studies in the journal Nature.
Study Suggests Possible Way to ‘Smac’ Cancer News

Study Suggests Possible Way to ‘Smac’ Cancer

In a new study, researchers at Dana-Farber Cancer Institute used cryo-electron microscopy to reveal for the first time how one IAP, a protein called BIRC6, operates at a molecular level to inhibit programmed cell death.
Dana-Farber Led Study Leads to FDA Approval for Next-Generation Drug in Relapsed Chronic Lymphocytic Leukemia News

Dana-Farber Led Study Leads to FDA Approval for Next-Generation Drug in Relapsed Chronic Lymphocytic Leukemia

On Thursday, January 19, 2023, the FDA approved zanubrutinib, a next-generation BTK inhibitor for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Study Finds Racial Inequities in Access to Opioids Among Older Patients With Cancer Near End of Life News

Study Finds Racial Inequities in Access to Opioids Among Older Patients With Cancer Near End of Life

Older Black and Hispanic patients with advanced cancer are less likely to receive opioid medications for pain relief in the last weeks of life than White patients, a new study led by Dana-Farber Cancer Institute investigators found.
Research With a Worldwide Reach News

Research With a Worldwide Reach

Around the world, Dana-Farber's Susan F. Smith Center for Women's Cancers is known not just for its exceptional patient care, but also for the driving force its physician-scientists play in developing new paradigms of cancer treatment through pioneering research and clinical trials.
New International Partnership to Accelerate Search for Cancer Cures News

New International Partnership to Accelerate Search for Cancer Cures

Cancer patients in Australia and the United States will benefit from a new research-focused collaboration between the Peter MacCallum Cancer Centre and Dana-Farber Cancer Institute in Boston.

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