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Dana-Farber Research News 07.15.2025
This twice-monthly newsletter highlights recently published research where Dana-Farber faculty are listed as first or senior authors. The information is pulled from PubMed and this issue notes papers published from June 16 through June 30.
News
Modified Personalized Cancer Vaccine Generates Powerful Immune Response
Dana-Farber researchers designed a novel formulation and delivery approach for the NeoVax personalized cancer vaccine and observed strong vaccine-specific immune responses in patients with melanoma.
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Teen with Rare Sarcoma Enjoys Stellar Response on Clinical Trial
Like many teenagers, Isabella (Bella) Snow Fraser, 15, enjoys immersing herself in action role-play games online.
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Dana-Farber Report Shows Alarming Rise in Many Gastrointestinal Cancers in Young People
Dana-Farber experts report rising rates of colorectal, pancreatic, esophageal, and other less common GI cancers in people under 50 and point to important next steps.
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Dana-Farber Research News 07.01.2025
This twice-monthly newsletter highlights recently published research where Dana-Farber faculty are listed as first or senior authors. The information is pulled from PubMed and this issue notes papers published from June 1 through June 15.
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Novel Cancer Screening Test for Veterans Now Being Offered at Dana-Farber Cancer Institute
During their time of service, members of the U.S. Armed Forces face considerable risks while fulfilling their mission and protecting the country. However, a less visible risk to the wellbeing of U.S. military members and veterans is on the rise.
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Cell Density Speaks Volumes About Cancer Treatment Choices
As powerful as modern cancer medicines are, they don’t work for everyone. What if there were a quick test doctors could perform on an individual person’s cancer to help determine which approved treatment would work best for them?
News
Dana-Farber Research News 06.15.2025
This twice-monthly newsletter highlights recently published research where Dana-Farber faculty are listed as first or senior authors. The information is pulled from PubMed and this issue notes papers published from May 16 through May 31.
News
FDA Approves Immune Checkpoint Inhibitor Drug for Patients With Resectable Locally Advanced Head and Neck Cancer
Pembrolizumab, an immune checkpoint inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with resectable locally advanced head and neck squamous cell carcinoma whose tumors express PD-L1 [Combined Positive Score (CPS) ?1] as determined by an FDA-approved test.
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Double Negative in Cells Could Undermine PARP Inhibitors
There are two ways to fix things: the quick way and the careful one. In cancer, cells with BRCA1 mutations tend to choose the quick fix, leaving them vulnerable to medicines like PARP inhibitors.
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ARC-20 Study Presented by Toni Choueiri, MD.
Toni Choueiri, MD, of Dana-Farber Cancer Institute presents first results from the ARC-20 trial evaluating casdatifan (HIF-2 inhibitor) + cabozantinib (VEGF TKI) in metastatic clear cell kidney cancer.
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TRADE Study Presented by Erica Mayer, MD.
Dr. Erica Mayer shares results from the TRADE study showing a successful abemaciclib dose escalation strategy in patients with HR+ breast cancer.