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Study Identifies Novel Target for Pediatric Neuroblastoma News

Study Identifies Novel Target for Pediatric Neuroblastoma

Researchers at Dana-Farber Cancer Institute have identified a protein complex that is required for the growth of a high-risk form of childhood brain cancer called MYCN-amplified neuroblastoma.
Telehealth Can Significantly Reduce Greenhouse Gas Emissions Associated with Cancer Care, Study Finds News

Telehealth Can Significantly Reduce Greenhouse Gas Emissions Associated with Cancer Care, Study Finds

Telemedicine visits for cancer care may not only be more convenient and easier to schedule than in-person appointments, they're also better for the planet, new research by Dana-Farber Cancer Institute scientists shows.
Science Behind Targeted Drug for Pediatric Brain Cancer Has Dana-Farber Roots News

Science Behind Targeted Drug for Pediatric Brain Cancer Has Dana-Farber Roots

Two separate research teams had discovered a genetic driver for the most common of childhood brain tumors called pediatric low-grade glioma.
Dana-Farber Cancer Institute Researchers Join Global Cancer Grand Challenges Team Taking on Solid Tumors in Children News

Dana-Farber Cancer Institute Researchers Join Global Cancer Grand Challenges Team Taking on Solid Tumors in Children

Dana-Farber Cancer Institute's Scott Armstrong, MD, PhD, Benjamin Ebert, MD, PhD, Eric Fischer, PhD, Cigall Kadoch, PhD, and Kimberly Stegmaier, MD, are part of a global, interdisciplinary team of researchers, called Team PROTECT, that has been selected to receive a Cancer Grand Challenges award. The award, of up to $25 million over five years, will be used to tackle solid tumors in children.
Dana-Farber/Boston Children's Again Ranked Among the Best Pediatric Cancer Programs in the Nation News

Dana-Farber/Boston Children's Again Ranked Among the Best Pediatric Cancer Programs in the Nation

U.S. News & World Report has named Dana-Farber/Boston Children's Cancer and Blood Disorders Center the #2 pediatric program in the nation in its 2023-24 Best Children's Hospitals report.
Three of the World’s Top Research Institutions Join Forces to Drive Progress Against Pediatric Cancer News

Three of the World’s Top Research Institutions Join Forces to Drive Progress Against Pediatric Cancer

Large-scale collaboration will leverage each institution’s expertise and infrastructure to advance understanding of the biological basis of pediatric cancers, identify new vulnerabilities of these diseases and accelerate cures globally.
Study Shows That Genomic Tumor Profiling of Pediatric Tumors Can Enhance Clinical Care News

Study Shows That Genomic Tumor Profiling of Pediatric Tumors Can Enhance Clinical Care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.
Dana-Farber/Boston Children's Again Named Top Pediatric Cancer Program News

Dana-Farber/Boston Children's Again Named Top Pediatric Cancer Program

U.S. News & World Report has named Dana-Farber/Boston Children's Cancer and Blood Disorders Center #1 in the nation in its 2022-23 Best Children's Hospitals report. Dana-Farber/Boston Children's has been recognized as one of the top three pediatric cancer centers in the country each year since the ranking's inception, earning more #1 rankings than any other program.
Race, Ethnicity, and Poverty Linked to Worse Outcomes in Children Treated for High-Risk Neuroblastoma News

Race, Ethnicity, and Poverty Linked to Worse Outcomes in Children Treated for High-Risk Neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.
Researchers Identify Promising Drug Target in Pediatric Neuroblastoma News

Researchers Identify Promising Drug Target in Pediatric Neuroblastoma

Dana-Farber scientists have now teased apart the relationship between the proteins EP300 and CBP — to discover that EP300 is critical for a high-risk form of pediatric neuroblastoma.
Dana-Farber/Boston Children’s Exceeds Expected Outcomes for Stem Cell Transplants News

Dana-Farber/Boston Children’s Exceeds Expected Outcomes for Stem Cell Transplants

Dana-Farber/Boston Children’s Cancer and Blood Disorders Center was ranked as one of 15 transplant centers in the country that performed above the expected survival rate, according to a new report.
Genetic Testing, Precision Therapy Spell Success for Young Patient with Rare Syndrome News

Genetic Testing, Precision Therapy Spell Success for Young Patient with Rare Syndrome

In a recent case study in the New England Journal of Medicine, researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center describe how a drug targeting the genetic roots of the patient’s condition — an agent based on Nobel Prize-winning research by a Dana-Farber scientist — has caused new tumors in the patient to shrivel, her high blood pressure and headaches to ease, and her polycythemia to relent.

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