ESMO Congress 2025

Review videos and news releases from Dana-Farber physician-scientists at the ESMO Congress 2025.
Dana-Farber Cancer Institute's Dr. Pasi Jänne details FLAURA2 which found first-line osimertinib + platinum pemetrexed chemotherapy improved overall survival vs. monotherapy in EGFR mutated non-small cell lung cancer, including poorer prognosis patients.
Dana-Farber Cancer Institute's D. Wenxin (Vincent) Xu shares research suggesting a blood test measuring levels of the KIM-1 biomarker could help assess the burden of disease in advanced kidney cancer and predict outcomes during first-line treatment.
Dr. Sara Tolaney details research in The New England Journal of Medicine showing the ADC sacituzumab govitecan improved outcomes for patients with advanced triple-negative #BreastCancer ineligible for immune checkpoint inhibitors.
Dana-Farber's Dr. Robert Haddad says research shows the combination of a PD1 with anti-LAG3 +/- anti-TIM3 does not improve outcomes in metastatic disease, raising the question of whether to look at this combo earlier, in the neoadjuvant setting.
News Releases
- Chemotherapy Combination Boosts Overall Survival in Patients with EGFR-mutant Non-Small Cell Lung Cancer
- Novel Treatment Combination Improves Progression-Free Survival in Metastatic, Estrogen-Receptor-Positive HER-2-Negative Breast Cancer
- ADC Improves Outcomes for Patients with Advanced Triple-Negative Breast Cancer Who are Ineligible for Immune Checkpoint Inhibitors
- Blood Test Guides Post-Surgical Immunotherapy for Muscle-Invasive Bladder Cancer
Featured Speakers
- Dana-Farber Oral Abstract Presentation Schedule at ESMO Congress 2025
- Keynote Lecture: Catherine Wu, MD on Therapeutic cancer vaccines: Clinical perspectives. October 19, 2025
- ESMO Congress 2025 Posters and ePoster presentations and abstracts, featuring Dana-Farber physician-scientists
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