William G. Kaelin Jr., MD won the Nobel Prize for discovering how cancer grows and multiplies by hijacking the body’s oxygen-sensing system, which led to a new class of oxygen-regulating drugs. Dr. Kaelin’s discovery has been effective against kidney cancer and is influencing new therapies for other cancers, heart disease, anemia, macular degeneration, and more. See more of Dana-Farber's Momentum of Discovery
chevron_right mm hmm, mm hmm. Mhm. 2015 headed down to parents weekend to see my oldest daughter at college. I ran into the house to go to the bathroom, blood in the urine and an indication that I had a tumor in the right kidney. It's a day that changed our life when I was a young clinician. I thought kidney cancer would perhaps be one of the last cancers where we would make progress at the Bigg clinical meetings. Kidney cancer is usually a pretty hot topic because thankfully we have made some progress years ago, there was one protocol for guys like me Now, there's basically 17 FADA approved protocols for folks like me fighting kidney cancer. And that's all because of the great work of folks like Bill calin and dr Tony Ferreri. My work relates in part to how tumors can derive a blood supply in order to grow. I knew if we could just understand finally how cells and tissues sensed and responded to oxidant, this would have implications again for many diseases. So what my fellow Laureates and I discover was the molecular circuit that all the cells and tissues in your body used to sense and respond to changes an oxidant. I'm just so blessed to be working with the dream team that I have. The dana Farber. I have a Nobel Prize winning researcher, Dr Bill calin, part of my arsenal. If you're lucky enough to be at a place like the dana Farber Cancer Institute. The scientists around you make you better because they're asking questions. They're probing your ideas. I am pushing you to do better. I think that's part of the secret sauce. Every day that goes by. We have more and more opportunity to find a more specific protocol that can help folks like me. The pace of discovery in the pace of developing these new drugs is really accelerating. I come to work every day excited to see the next result. And it's not just the quality patient care. It's the research, it's the innovation, it's the moving forward in this crazy, crazy, crazy battle and that's why I'm still standing today. Could scientists should always believe the most important thing they're ever going to discover still lies ahead of them. My goal is to be one of many, many, many people trying to push the field forward. So we hopefully get to the day when the waiting rooms are empty. Wow. Mhm, mm hmm, mm hmm, mm hmm mm hmm, mm hmm.