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Double Negative in Cells Could Undermine PARP Inhibitors
There are two ways to fix things: the quick way and the careful one. In cancer, cells with BRCA1 mutations tend to choose the quick fix, leaving them vulnerable to medicines like PARP inhibitors.
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TRADE Study Presented by Erica Mayer, MD.
Dr. Erica Mayer shares results from the TRADE study showing a successful abemaciclib dose escalation strategy in patients with HR+ breast cancer.
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Talazoparib + Tazemetostat Presented by Atish Choudhury, MD, PhD.
Dr. Atish Choudhury presented clinical trial results evaluating the combination of talazoparib and tazemetostat in advanced prostate cancer.
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Phase 2 PROSPECT Study Presented by Lakshmi Nayak, MD.
Lakshmi Nayak, MD presented results from a phase 2 PROSPECT study focused on tirabrutinib and it's effect on patients with relapsed or refractory primary central nervous system lymphoma.
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Checkmate 214 Presented by Toni Choueiri, MD.
Dr. Toni Choueiri shares groundbreaking 9-year results from the CHECKMATE-214 trial.
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DESTINY-Breast09 Presented by Sara Tolaney, MD, MPH.
Dr. Sara Tolaney of Dana-Farber shares pivotal results from the DESTINY-Breast09 phase 3 trial.
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Stereotactic Radiation Presented by Ayal Aizer, MD.
Dr. Ayal Aizer of Dana-Farber Brigham Cancer Center presents results at #ASCO25 from a phase 3 trial on stereotactic radiation.
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ReACT 1.0 Study Presented by Glenn Hanna, MD.
Dr. Glenn Hanna presented phase 2 data suggesting that circulating HPV DNA could serve as a real-time biomarker to guide treatment intensity in HPV-positive oropharyngeal cancer.
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NSCLC Study Presented by Julia Rotow, MD.
Dr. Julia Rotow presented results from a study using a cell-free DNA (cfDNA)-guided strategy to personalize first-line treatment for advanced non-small cell lung cancer.
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ARC-20 Study Presented by Toni Choueiri, MD.
Toni Choueiri, MD, of Dana-Farber Cancer Institute presents first results from the ARC-20 trial evaluating casdatifan (HIF-2 inhibitor) + cabozantinib (VEGF TKI) in metastatic clear cell kidney cancer.
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Letrozole + Abemaciclib + Metformin Study Presented by Panos Konstantinopoulos, MD, PhD.
Dr. Panos Konstantinopoulos presented the first study of a triplet therapy combining letrozole, abemaciclib, and metformin in any cancer type.
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PRISM-AC Study Presented by Abby Rosenberg, MD, MS.
A new psychosocial intervention is showing promising results for adolescents and young adults (AYA) facing advanced cancer.