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Researchers Uncover Key Actor in Spread of Breast Cancer to the Brain
When breast cancer metastasizes, it often heads for the brain, where it can be exceptionally difficult to root out. The key to preventing the spread of the cancer, or thwarting it if it does reach the brain, is to understand the mechanism that turns stationary tumor cells into nomadic intruders.
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Expanding Possibilities - Researchers Dive Deep to Identify Exceptional Responders
In 2020, data from a clinical trial of patients with metastatic HER2-positive breast cancer caught the attention of Dana-Farber breast oncologist Heather Parsons, MD, MPH. She noticed what she describes as a "long tail."
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Dana-Farber Research News 9.15.2024
This twice-monthly newsletter highlights recently published research where Dana-Farber faculty are listed as first or senior authors. The information is pulled from PubMed and this issue notes papers published from August 16 through August 31.
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High-Dose Vitamin D3 Does Not Provide Benefit for Metastatic Colorectal Cancer
SOLARIS (Alliance A021703): A multicenter double-blind phase III randomized clinical trial of vitamin D combined with standard chemotherapy plus bevacizumab in patients with previously untreated metastatic colorectal cancer.
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Breast Cancer Research: New Studies Show How Post-Treatment Lifestyle Choices Shape Long-Term Outcomes After Diagnosis
Three studies led by Dana-Farber Cancer Institute researchers have encouraging implications for patients with breast cancer.
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Long-term Metastatic Melanoma Survival Dramatically Improves on Immunotherapy
Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Dana-Farber Cancer Center and Weill Cornell Medicine investigators and their colleagues.
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Repeat Immune Checkpoint Inhibitor Therapy Not Recommended for Advanced Kidney Cancer
Tivozanib Plus Nivolumab vs Tivozanib Monotherapy in Patients with Renal Cell Carcinoma Following an Immune Checkpoint Inhibitor – Results of the Phase 3 TiNivo-2 Study
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Antibody-Drug Conjugate Found Effective Against Brain Metastases in Patients with HER2-Positive Breast Cancer
A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer.
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ESMO Congress 2024
Learn more about prostate, bladder and kidney cancer studies led by Dana-Farber presented at ESMO Congress 2024.
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Comprehensive Cancer Research from Dana-Farber Leads ESMO Congress 2024
Innovations in breast cancer, targeted therapies, antibody drug conjugates, and kidney cancer
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Ann Partridge Receives 2024 ESMO Award for Significant Contributions to Breast Cancer Research and Patient Care
The European Society for Medical Oncology (ESMO) recognized Ann Partridge, MD, MPH, of Dana-Farber Cancer Institute, as a recipient of the 2024 ESMO Award: Addressing the Unintended Consequences of Cancer Care.
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Adolescent Glioma Subtype Responds to CDK4/6 Inhibitor
CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.