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A Year of Advances in Genitourinary Cancer
Dana-Farber’s genitourinary cancer team is devoted to research that will advance patient care and improve patient’s lives. Recently, that research — all of it years in the making — has paid off with major achievements.
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What is a Menin Inhibitor?
Menin, a protein located in the nucleus of various human cell types, often functions as a tumor suppressor by inhibiting excessive cell growth and division.
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Dana-Farber Investigators Pinpoint Keys to Cell Therapy Response for Leukemia
Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transplant, will successfully move the patient into remission.
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Study Finds Care After Donor Stem Cell Transplant Can Be Safely Shared Between Transplant Centers and Local Oncologists
Patients undergoing a donor stem-cell transplant for leukemia or other blood-related cancer require months of specialized follow-up care, traditionally delivered at the center where they received their transplant – often a serious challenge for those who live far away.
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New Research Shows Inherited Genetic Variants Increase Risk of Certain Pediatric Cancers
New research from Dana-Farber Cancer Institute has found that rare germline genetic abnormalities could increase the risk of childhood cancers such as neuroblastoma, Ewing sarcoma, and osteosarcoma.
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Turning Up the Heat: Dana-Farber Scientists Describe Key Molecular Shift in Brown Fat Cells
Brown fat is a specialized tissue that has developed a host of important functions over the course of evolution. One of the most critical: the ability to produce heat in response to low temperatures by burning energy.
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Early Detection and Interception Research Shows Promise at ASH
Dana-Farber Cancer Institute investigators are leading three separate studies with encouraging results related to the early detection and interception of multiple myeloma.
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Dana-Farber Cancer Institute Faculty Among World's Most Highly Cited Researchers
Dana-Farber Cancer Institute is proud to announce that 42 of its researchers have been named to the Highly Cited Researchers list of 2024, released today by the Institute for Scientific Information at Clarivate.
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Building in Access from the Start: Five Efforts by the Centers for Early Detection and Interception
Dana-Farber’s Centers for Early Detection and Interception, founded in 2023, aim to detect cancer early, when there is a greater chance of treating and curing that cancer.
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Dana-Farber Researchers ‘Hijack’ Gut Bacteria to Design Novel Form of Cancer Immunotherapy
Tumors are experts at dodging the immune system. This evasion not only helps to ensure their survival, but also has important implications for treatment.
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Rapid Blood Cancer Diagnostic Could Speed Decisions and Save Lives
Researchers at Dana-Farber Cancer Institute have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions.
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Study Finds Unexpected Role for Odd-Man-Out Member of CDK Protein Family
In the family of cyclin-dependent kinase (CDK) proteins, CDK5 always seemed to be a misfit. Despite being structurally similar to other CDKs, and despite the “cyclin” in its name, it did not participate in the family business of ushering cells through the cycle of growth and division.