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The Gene Fixer
For five decades, Stuart Orkin has harnessed new genetic tools to transform care for blood disorders – helping make sickle cell and beta thalassemia curable.
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Dana-Farber Research Uncovers Approach to Activating the Immune System Against Metastatic Breast Cancer
Cancer spreads, or metastasizes, when tumor cells shed from a primary solid tumor, for example in the breast, and embed in other organs, such as the lung, liver, and brain, and begin to grow.
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Dana-Farber, Gustave Roussy to Host Fifth Transatlantic Exchange in Oncology Focused on Cancer Drug Innovation
Dana-Farber Cancer Institute will host the Fifth Transatlantic Exchange in Oncology on Friday, March 27, 2026, bringing together leading cancer researchers and clinicians from the United States and Europe to explore transatlantic innovations in cancer drug research.
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Making Breakthroughs in ALL From Youth to Adulthood
When Ann Carroll was diagnosed with cancer at age 28, her dream to get married and have a baby felt out of reach. Now, seven years later and cancer-free, she is living that dream with her husband and their 7-month-old son, Teddy.
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Cell-Death Safety Net a Potential New Cancer Target
In the rare event that an elevator cable breaks, modern buildings have additional fail-safe mechanisms. For example, counterweight and mechanical brakes prevent the car from plummeting to the ground.
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Dana-Farber Research Helps Drive FDA Label Update for Primary CNS Lymphoma
Change removes prior exclusion and may expand access to CAR T-cell therapy for eligible relapsed or refractory patients
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Three Dana-Farber Cancer Institute scientific leaders elected as Fellows of the American Association for Cancer Research (AACR) Academy Class of 2026
Dr. Alice Shaw, Dr. Kimberly Stegmaier and Dr. Matthew Vander Heiden have been elected as Fellows of the American Association for Cancer Research (AACR) Academy Class of 2026.
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Taming Chronic Inflammation
Dana-Farber researchers explore how lifestyle choices may help reduce cancer risk and improve outcomes
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ADC Combination Outperforms Standard Treatment of Advanced Triple-Negative Breast Cancer
In patients with advanced triple negative breast cancer, treatment with the antibody-drug conjugate sacituzumab govitecan plus pembrolizumab led to durable responses and improved progression free survival compared to the current standard treatment, according to results of the ASCENT-04/KEYNOTE-D19 study, published today in the New England Journal of Medicine.
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Dana-Farber Researchers Discover How Major Nuclear Protein Complexes Control Specialized Gene Regulation in Cancer and Beyond
The SWI/SNF Ig-Fold for Transcription Factor Interactions or ‘SWIFT’ domain on mSWI/SNF chromatin remodeling complexes engage proteins called transcription factors (TFs) to target specialized genes along human DNA—often cancer-promoting genes—flagging SWIFT-TF interactions as promising new therapeutic targets.
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Twenty-Five Years of Progress in Cancer
As we close out the first quarter of the twenty-first century, it isn’t hard to notice how much the world has changed since the year 2000. Smartphones. Social media. Artificial intelligence.
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Dana-Farber Study Highlights the Need for Faster, More Accurate Diagnosis of Rare Cancer
A new study from Dana-Farber Cancer Institute finds that patients with NUT carcinoma (NC), an aggressive squamous cell lung or head and neck cancer, often face delays in diagnosis—delays that can prevent them from receiving the right treatment or joining clinical trials.